Extremely volatile, colorless liquid with a chloroformlike odor. TFK forms a hydrate with water (mp 51 °C), which decomposes on exposure to the air.
Chemical reactions and applications
TFK is a biologically active and blood pressure reducing substance. Because of its acidity, which is higher than that of acetone, relatively mild basic conditions are sufficient to produce the enclate required for a C-C bonding. TFK is therefore ideal for use as a building block for carbo- and heterocycles containing CF3 groups. Moreover, the -I effect of the CF3 group increases the electrophilia of the carbonyl C atom. Here too this opens up numerous possibilities for synthetic applications.
Delivery and handling
TFK is supplied in high-grade steel containers. TFK is a highly volatile, inflammable substance (flash point -30°C). The inhaling of vapours and skin contact must be avoided. Good ventilation and deaeriation of the workplace must be provided.
Extremely volatile, colorless liquid with a chloroformlike odor. TFK forms a hydrate with water (mp 51 °C), which decomposes on exposure to the air.
