Trifluoroacetic acid ethylester (TFAEt) is colorless and a very volatile liquid, slightly pungent and easily inflammable.
Chemical reactions and applications The esters of trifluoroacetic acid are specialties in organic synthesis. The chemical reactions are mainly based on a nucleophilic substitution of the ester and lead to formation of trifluoroacylated compounds. The most important reactions are the ester condensation for the synthesis of β-diketones, the trifluoroacylation of amines, the reaction with phosphine derivatives and the reaction with organometallics for the synthesis of fluorinated ketones and fluorinated tert. alcohols.
Delivery and handling
TFAEt is delivered in polyethylene-lined metal drums. It is an inflammable, irritante liquid. When handling trifluoroacetic acid ethylester, contact with skin and inhalation of the vapours of these extremely volatile compounds must be avoided at all cost and protective clothing must be worn. Affected parts of the body must be immediately rinsed with plenty of water. A well ventilated working area is essential. Further trifluoroacetic acid esters on request.
TFAEt) is colorless and a very volatile liquid, slightly pungent and easily inflammable.
